Three reasons Twist Bioscience and Cloudflare should talk.

Point of view

Modernize global application delivery and unify DNS, API, ecommerce, image, and email protection around Twist's digital ordering experience through bounded migrations.

Why Cloudflare?
Why now?

Cloudflare can replace the visible Akamai delivery layer and unify DNS, API, ecommerce, image, and email protection around Twist's global ordering experience through bounded,... Customers increasingly enter Twist through catalogs, codon tools, ecommerce, and APIs.

DNS / HTTP recon

www and images use Akamai edgekey CNAMEs, the apex is in Akamai address space, and no cf-ray was observed during recon.

CSP / page inspection

api.twistbioscience.com is public, and the homepage loads ecommerce.twistdna.com, catalog.twistdna.com, and...

DNS / HTTP recon

The domain's authoritative nameservers are Amazon Route 53 awsdns hostnames.

Three highest-impact use cases

What to prove together

Prioritized by business impact and strength of public evidence.

01 Business outcome

Modernize global application delivery

Cloudflare CDN + WAF + DDoS Protection + Load Balancing What Cloudflare does

A phased route migration can consolidate delivery and application security while preserving current origins and customer-ordering applications.

Bounded pilot

Proxy one low-risk hostname or route with the current origin preserved for rollback.

Measure

p95 latency, cache hit ratio, origin offload, blocked attacks, operating cost.

02 Business outcome

Protect API and ordering workflows

API Shield + Bot Management + Turnstile + Rate Limiting What Cloudflare does

Discover schemas and traffic first, then apply mTLS, schema validation, bot, and abuse controls to selected order and integration endpoints.

Bounded pilot

Discover one bounded API or agent workflow, then enforce schema, identity, and rate policy.

Measure

Discovered endpoints, blocked abuse, policy coverage, origin load, p95 latency.

03 Business outcome

Unify DNS and application delivery

Cloudflare Authoritative DNS + DNSSEC + Load Balancing + Health Checks What Cloudflare does

Move DNS through a staged secondary or delegated approach, then manage traffic steering and application security from one control plane.

Bounded pilot

Import one low-risk zone, validate records, DNSSEC, and rollback before delegation.

Measure

Query latency, availability, change time, failed lookups, retired DNS cost.

Discover
Prove
Scale

30-day DiscoverInventory Akamai properties and service commitments, Route 53 zones, origin dependencies, API and ordering endpoints, image traffic, and...

60-day ProveProxy a low-risk content or image route through Cloudflare, import DNS records without changing authority, test API discovery, and run Area 1...

Scale by evidenceMove validated www or image traffic, stage authoritative DNS cutover with rollback, enable selected API controls, and decide email-security...

Compact value model

BaselineCurrent vendor run-rate + egress/compute + operating hours.

ValueRetired overlap + avoided load/incidents + hours returned.

DecisionAnnualized pilot delta - Cloudflare run-rate - one-time migration cost.

Cloudflare
overview

ProtectWAF, DDoS, bot, API and email security

AccelerateCDN, DNS, load balancing and smart routing

ConnectZero Trust, private access and secure networking

BuildWorkers, R2, AI and developer services